
All three brothers became medical doctors, but the eldest, Arthur, showed a particular talent for advertising, combining both his passions by joining and later owning William Douglas McAdams Inc., an advertising firm that exclusively handled medicinal clients and pioneered the technique of advertising medication directly to doctors. Summary Īrthur, Mortimer, and Raymond Sackler were children of Jewish immigrants that were raised in Brooklyn. The book followed Keefe's 2017 article on the Sackler family in The New Yorker, titled The Family That Built an Empire of Pain. The book examines the history of the Sackler family, including the founding of Purdue Pharma, their role in the marketing of pharmaceuticals, and the family's central role in the opioid epidemic.

Empire of Pain: The Secret History of the Sackler Dynasty is a 2021 book by Patrick Radden Keefe.
